Concepción Peraire Selected Research

BN 80927

8/2012

Population pharmacokinetic/pharmacodynamic modeling of drug-induced adverse effects of a novel homocamptothecin analog, elomotecan (BN80927), in a Phase I dose finding study in patients with advanced solid tumors.

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Concepción Peraire Research Topics

Disease

4	Neoplasms (Cancer) 08/2012 - 07/2011
4	Acromegaly 04/2012 - 10/2005
3	Neutropenia 08/2012 - 06/2006
2	Nausea 08/2012 - 01/2006
2	Vomiting 08/2012 - 01/2006
1	Breast Neoplasms (Breast Cancer) 04/2015
1	Prostatic Neoplasms (Prostate Cancer) 09/2012
1	Asthenia 08/2012
1	Osteosarcoma (Osteogenic Sarcoma) 02/2009
1	Headache (Headaches) 01/2006
1	Dizziness (Lightheadedness) 01/2006
1	Hepatic Insufficiency 01/2006

Drug/Important Bio-Agent (IBA)

4	lanreotide (Somatuline)FDA Link 04/2012 - 10/2005
3	irosustatIBA 04/2015 - 07/2011
3	Pharmaceutical PreparationsIBA 08/2012 - 02/2009
3	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2009 - 10/2005
2	Delayed-Action PreparationsIBA 09/2012 - 10/2005
2	Hormones (Hormone)IBA 07/2012 - 07/2011
2	Steryl-Sulfatase (Steroid Sulfatase)IBA 07/2012 - 07/2011
2	diflomotecanIBA 10/2011 - 06/2006
1	Triptorelin Pamoate (Trelstar)FDA Link 09/2012
1	Testosterone (Sustanon)FDA Link 09/2012
1	BN 80927IBA 08/2012
1	homocamptothecinIBA 08/2012
1	Growth Hormone (Somatotropin)IBA 04/2012
1	Insulin-Like PeptidesIBA 04/2012
1	Insulin-Like Growth Factor I (IGF-1)IBA 04/2012
1	N- (3- chloro- 7- indolyl)- 1,4- benzenedisulphonamide (E7070)IBA 10/2011
1	Methotrexate (Mexate)FDA LinkGeneric 02/2009
1	2,5-dichloro-4-bromophenol (B 2)IBA 01/2006

Therapy/Procedure

3	Therapeutics 07/2012 - 10/2005
1	Castration 09/2012
1	Intravenous Infusions 08/2012
1	Drug Therapy (Chemotherapy) 10/2011
1	Intravenous Administration 02/2009
1	Injections 10/2005